Molecular mechanism of α2β1 integrin interaction with human echovirus 1
نویسندگان
چکیده
منابع مشابه
Molecular Mechanism of α2β1 Integrin Interaction with Human Echovirus 1
Thank you for submitting your manuscript for consideration by the EMBO Journal. First of all, please let me apologise for the length of time taken to get back to you with a decision this was due firstly to some difficulty in finding three appropriate referees, and secondly to a delay in receiving the final report. However, your manuscript has now been seen by three referees whose comments are e...
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We have previously shown that soluble collagen and a human pathogen, echovirus 1 (EV1) cluster α2β1 integrin on the plasma membrane and cause their internalization into cytoplasmic endosomes. Here we show that cholesterol plays a major role not only in the uptake of α2β1 integrin and its ligands but also in the formation of α2 integrin-specific multivesicular bodies (α2-MVBs) and virus infectio...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2009
ISSN: 0261-4189,1460-2075
DOI: 10.1038/emboj.2009.326